中文簡介

環(huán)境毒理學(xué)和藥理學(xué)發(fā)表關(guān)于(人類和獸醫(yī))藥物的毒性和藥理作用以及動物和人的環(huán)境污染物的研究結(jié)果。特別感興趣的是：毒性的分子機制，生物轉(zhuǎn)化和毒代動力學(xué)（包括毒代動力學(xué)模型），分子、生化和生理機制解釋了物種和個體之間敏感性的差異，病理生理模型的特征和涉及效果發(fā)展的機制以及可用于研究人和動物暴露和影響的生物標(biāo)志物的鑒定。除了長篇論文、簡短通訊、長篇評論和小型評論外，環(huán)境毒理學(xué)和藥理學(xué)還將發(fā)表對特殊問題領(lǐng)域的深入評估。后一種出版物的篇幅可超過一篇完整論文的三至四倍。一項基本要求是在有關(guān)領(lǐng)域主要專家的國際小組主持下進行評估。所審查的資料可以是已經(jīng)發(fā)表的數(shù)據(jù)，也可以是在合作研究方案框架內(nèi)取得的新數(shù)據(jù)。所列經(jīng)費還用于接受關(guān)于(類)化合物、毒性或機理的小型審查，辯論屬于該期刊范圍內(nèi)的迅速發(fā)展領(lǐng)域的最新進展。該期刊的目錄現(xiàn)在可以通過電子郵件提前發(fā)布，作為埃爾塞維爾科學(xué)的免費內(nèi)容直接服務(wù)的一部分。請發(fā)電子郵件給cdhelp@elsevier.co.uk，了解有關(guān)這項服務(wù)的更多信息。

　　英文簡介

Environmental Toxicology and Pharmacology publishes the results of studies concerning toxic and pharmacological effects of (human and veterinary) drugs and of environmental contaminants in animals and man.Areas of special interest are: molecular mechanisms of toxicity, biotransformation and toxicokinetics (including toxicokinetic modelling), molecular, biochemical and physiological mechanisms explaining differences in sensitivity between species and individuals, the characterisation of pathophysiological models and mechanisms involved in the development of effects and the identification of biological markers that can be used to study exposure and effects in man and animals. In addition to full length papers, short communications, full-length reviews and mini-reviews, Environmental Toxicology and Pharmacology will publish in depth assessments of special problem areas. The latter publications may exceed the length of a full length paper three to fourfold. A basic requirement is that the assessments are made under the auspices of international groups of leading experts in the fields concerned. The information examined may either consist of data that were already published, or of new data that were obtained within the framework of collaborative research programmes. Provision is also made for the acceptance of minireviews on (classes of) compounds, toxicities or mechanisms, debating recent advances in rapidly developing fields that fall within the scope of the journal.The table of contents for this journal is now available pre-publication, via e-mail, as part of the free ContentsDirect service from Elsevier Science. Please send an e-mail message to cdhelp@elsevier.co.uk for further information about this service.

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